Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332534 | 0.83 | MAPT (0.51) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL1013587 | 0.81 | MAPT (0.53) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL28195331 | 0.80 | MAPT (0.49) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL1201707 | 0.80 | TYMS (0.56) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL28199916 | 0.80 | MAPT (0.45) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL3947023 | 0.76 | MAPT (0.45) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL11370268 | 0.76 | PARP1 (0.51) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL15228497 | 0.76 | MAPT (0.45) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL1895139 | 0.76 | MEN1 (0.56) | MAPTTDP1APEX1MEN1KMT2A | |
| SCHEMBL6813356 | 0.76 | NPSR1 (0.46) | MAPTTDP1APEX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298904-A1 | Xylanases, nucleic acids encoding them and methods for making and using them | Verenium Corporation (US) | 2011-03-23 | — | — | EP | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |