Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | CHUK | O15111 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766156 | 0.76 | IKBKB (0.34) | IKBKBCHUKIDO1 | |
| SCHEMBL12145188 | 0.74 | IKBKB (0.37) | IKBKBCHUK | |
| SCHEMBL24654884 | 0.68 | PDE10A (0.33) | IKBKBCHUK | |
| SCHEMBL14341732 | 0.64 | — | — | |
| SCHEMBL23029843 | 0.64 | KDM4E (0.38) | IKBKBCHUKIDO1 | |
| SCHEMBL24857521 | 0.58 | KDM4E (0.33) | IKBKBCHUKIDO1 | |
| SCHEMBL24858410 | 0.58 | KDM4E (0.33) | IKBKBCHUKIDO1 | |
| SCHEMBL24992635 | 0.57 | IDO1 (0.35) | IKBKBCHUKIDO1 | |
| SCHEMBL10001568 | 0.57 | — | — | |
| SCHEMBL822679 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426440-B2 | Indolymaleimide derivatives | NOVARTIS AG (CH) | 2013-04-23 | — | — | US | disclosed |