⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444358 | 0.78 | — | — | |
| SCHEMBL12055110 | 0.76 | — | — | |
| SCHEMBL26539826 | 0.76 | — | — | |
| SCHEMBL13444395 | 0.75 | — | — | |
| SCHEMBL13444400 | 0.73 | — | — | |
| SCHEMBL18165618 | 0.73 | — | — | |
| SCHEMBL13444402 | 0.71 | — | — | |
| SCHEMBL15705506 | 0.69 | — | — | |
| SCHEMBL15705489 | 0.68 | ATM (0.31) | — | |
| SCHEMBL13931726 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11813267-B2 | DNA-PK inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-11-14 | — | — | US | disclosed |
| US-8426440-B2 | Indolymaleimide derivatives | NOVARTIS AG (CH) | 2013-04-23 | — | — | US | disclosed |