Sugi Predict

Sugi Predict / Compounds / SCHEMBL14879022

SCHEMBL14879022

SCHEMBL14879022

CC(C)C(c1ccc(C(C)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)N1CCC(F)(F)CC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CETP P11597 19/20 0.39
▸ TACR1 P25103 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526520 0.96 CETP (0.42) CETPTACR1
SCHEMBL5526664 0.91 CETP (0.41) CETPTACR1
SCHEMBL14879034 0.90 CETP (0.38) CETP
SCHEMBL5533482 0.88 CETP (0.43) CETPTACR1
SCHEMBL4977039 0.88 CETP (0.43) CETPTACR1
SCHEMBL4976752 0.88 CETP (0.43) CETPTACR1
SCHEMBL5535787 0.88 CETP (0.43) CETPTACR1
SCHEMBL5528772 0.86 CETP (0.41) CETP
SCHEMBL5532308 0.86 CETP (0.41) CETP
SCHEMBL5525598 0.86 CETP (0.41) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994015-B1 DIBENZYL AMINE DERIVATIVES AS CETP INHIBITORS PFIZER PROD INC (US) 2013-04-24 — — EP disclosed