⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817300 | 0.53 | — | — | |
| SCHEMBL600393 | 0.53 | — | — | |
| Water SCHEMBL28873582 | 0.47 | — | — | |
| SCHEMBL352871 | 0.47 | — | — | |
| SCHEMBL5533417 | 0.47 | — | — | |
| SCHEMBL30107638 | 0.47 | — | — | |
| SCHEMBL6206429 | 0.47 | — | — | |
| SCHEMBL29525891 | 0.45 | KDM4E (0.40) | — | |
| SCHEMBL29525411 | 0.45 | KDM4E (0.40) | — | |
| SCHEMBL37684 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633771-B1 | MACROLIDE-CONJUGATES WITH ANTI-INFLAMMATORY ACTIVITY | GLAXOSMITHKLINE ZAGREB (HR) | 2009-07-15 | — | — | EP | claimed |
| US-4119631-A | Penicillins and their preparation | E. MERCK, PATENTABTEILUNG (DE) | 1978-10-10 | — | — | US | claimed |
| CN-113912476-A | Method for depolymerizing polycarbonate material by using amine alcohol system | 中国科学院青岛生物能源与过程研究所 | 2022-01-11 | — | — | CN | disclosed |
| CN-106917151-B | Ultraviolet absorption fabric | 杭州琪瑶纺织有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-107021933-B | A method of N- aryl oxazolidine -2- ketone compounds are synthesized by ionic liquid-catalyzed | 华东师范大学 | 2019-09-10 | — | — | CN | disclosed |
| EP-3201216-A1 | METHOD FOR PEPTIDE SYNTHESIS AND APPARATUS FOR CARRYING OUT A METHOD FOR SOLID PHASE SYNTHESIS OF PEPTIDES | Technische Universität Darmstadt (DE) | 2017-08-09 | — | — | EP | disclosed |
| CN-107021933-A | It is a kind of by the ionic liquid-catalyzed method for synthesizing N- Fang Ji oxazolidine -2- ketone compounds | 华东师范大学 | 2017-08-08 | — | — | CN | disclosed |
| WO-2016050764-A1 | METHOD FOR PEPTIDE SYNTHESIS AND APPARATUS FOR CARRYING OUT A METHOD FOR SOLID PHASE SYNTHESIS OF PEPTIDES | Technische Universität Darmstadt (DE) | 2016-04-07 | — | — | WO | disclosed |
| EP-1838315-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | SANOFI SA (FR) | 2014-03-12 | — | — | EP | disclosed |
| EP-2289888-A3 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-07-13 | — | — | EP | disclosed |
| EP-2289887-A3 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-07-06 | — | — | EP | disclosed |
| US-7521473-B2 | Inhibitors of protein tyrosine phosphatase 1B | WYETH (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080058328-A1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, PHARMACEUITCAL COMPOSITIONS COMPRISING THEM AND THERAPEUTIC METHODS FOR THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| JP-2008013568-A | METHOD FOR PRODUCING β-AMINO-α-HYDROXYCARBOXYLIC ACID AMIDE | DEGUSSA GMBH | 2008-01-24 | — | — | JP | disclosed |
| EP-1876168-A1 | Method for manufacturing beta amino alpha hydroxy carboxylic acid amides | Evonik Degussa GmbH (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1295876-A4 | EPOXYCARBOXYLIC ACID AMIDES, AZIDES AND AMINO ALCOHOLS AND PROCESSES FOR PREPARATION OF ALPHA-KETO AMIDES BY USING THEM | KOBAYASHI NOBUO (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20050203087-A1 | Inhibitors of protein tyrosine phosphatase 1B | WYETH | 2005-09-15 | — | — | US | disclosed |
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |
| JP-2002179664-A | EPOXYCARBOXYLIC ACID AMIDE DERIVATIVE | SEIKAGAKU KOGYO CO LTD | 2002-06-26 | — | — | JP | disclosed |
| WO-2002002546-A1 | EPOXYCARBOXYLIC ACID AMIDES, AZIDES AND AMINO ALCOHOLS AND PROCESSES FOR PREPARATION OF α-KETO AMIDES BY USING THEM | SEIKAGAKU CORPORATION (JP) | 2002-01-10 | — | — | WO | disclosed |