Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1218751 | 0.71 | POLB (0.60) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL9906961 | 0.66 | POLB (0.45) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL1218625 | 0.66 | POLB (0.64) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL3199393 | 0.65 | POLB (0.44) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL18485392 | 0.64 | STAT3 (0.43) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL13839056 | 0.62 | CA1 (0.35) | ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL24303333 | 0.62 | POLB (0.42) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL17532439 | 0.62 | POLB (0.42) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL18017060 | 0.62 | POLB (0.40) | POLBLMNARAB9ASTAT3ALDH1A1 | |
| SCHEMBL9550333 | 0.61 | POLB (0.41) | POLBLMNARAB9ASTAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583678-A2 | Small molecule immunopotentiators and assays for their detection | Novartis Vaccines and Diagnostics, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |