Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780819 | 0.93 | HTR2A (0.49) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL13474589 | 0.90 | HTR2A (0.48) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL25135345 | 0.88 | HTR2A (0.49) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL14712301 | 0.87 | HTR2A (0.46) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL23915970 | 0.86 | HTR2A (0.44) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL17208858 | 0.83 | HTR2A (0.48) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL14607613 | 0.83 | HTR2A (0.50) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL22546645 | 0.82 | HTR2A (0.44) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL21097079 | 0.81 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL7080623 | 0.80 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694274-B1 | Glycopegylated granulocyte colony stimulating factor | BIOGENERIX AG (DE) | 2013-04-24 | — | — | EP | disclosed |