Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.42 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882674 | 0.87 | HDAC1 (0.44) | ANO1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL14875894 | 0.87 | HDAC1 (0.56) | ALDH1A1HPGDKDM4EPOLBMMP13 | |
| SCHEMBL14882770 | 0.86 | ANO1 (0.50) | ANO1ALDH1A1GRM4POLBHDAC8 | |
| Hydrochloric Acid SCHEMBL14876074 | 0.86 | HDAC1 (0.43) | ANO1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL14882660 | 0.86 | ANO1 (0.50) | ANO1ALDH1A1HPGDKDM4EGRM4 | |
| Hydrochloric Acid SCHEMBL14876023 | 0.85 | ANO1 (0.49) | ANO1ALDH1A1HPGDKDM4EGRM4 | |
| Hydrochloric Acid SCHEMBL14875798 | 0.85 | ANO1 (0.49) | ANO1ALDH1A1GRM4POLBHDAC8 | |
| SCHEMBL14882680 | 0.84 | ANO1 (0.49) | ANO1GRM4HDAC8MMP13HDAC1 | |
| Hydrochloric Acid SCHEMBL14876068 | 0.83 | ANO1 (0.48) | ANO1GRM4HDAC8MMP13HDAC1 | |
| SCHEMBL14882665 | 0.81 | ANO1 (0.49) | ANO1ALDH1A1GRM4POLBHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102601-A1 | Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease | F. HOFFMANN-LA ROCHE LTD (CH) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102601-A1 | Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease | TPMT, TYMP, HPRT1 | ANO1 3256/4885ALDH1A1 609/4885HPGD 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.