Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | INPP5D | Q92835 | 2/20 | 0.66 |
| ▸ | CDC25A | P30304 | 6/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27494141 | 0.82 | CDC25A (0.55) | CYP2D6CYP2C19INPP5DCDC25ACDC25B | |
| SCHEMBL12279525 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL21589991 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL16344584 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL23016826 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL24104271 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL1881196 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL23645781 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL21946613 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 | |
| SCHEMBL22712829 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102577-A1 | SHIP INHIBITORS AND USES THEREOF | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102577-A1 | SHIP INHIBITORS AND USES THEREOF | PPP5C, DUSP1, DUSP5 | CYP2D6 3990/4885CYP2C19 4686/4885INPP5D 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.