Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889562 | 0.94 | SCN9A (0.55) | SCN9ACYP2C9SCN5A | |
| SCHEMBL12505833 | 0.86 | SCN9A (0.59) | SCN9A | |
| SCHEMBL14889981 | 0.86 | SCN9A (0.56) | SCN9ACYP2C9SCN5A | |
| SCHEMBL319776 | 0.85 | SCN9A (0.56) | SCN9A | |
| SCHEMBL14889949 | 0.81 | SCN9A (0.60) | SCN9ACYP2C9SCN5A | |
| Trifluoroacetic Acid SCHEMBL14889704 | 0.79 | SCN9A (0.69) | SCN9ACYP2C9SCN5A | |
| SCHEMBL15646056 | 0.78 | SCN9A (0.42) | SCN9ACYP2C9SCN5A | |
| SCHEMBL15647636 | 0.77 | SCN9A (0.42) | SCN9ACYP2C9SCN5A | |
| SCHEMBL319725 | 0.77 | SCN9A (0.77) | SCN9A | |
| SCHEMBL22368003 | 0.76 | SCN9A (0.42) | SCN9ACYP2C9SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145407-B2 | Sulfonamide compounds | PFIZER LIMITED (GB) | 2015-09-29 | — | — | US | disclosed |
| EP-2590972-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2015-01-21 | — | — | EP | disclosed |
| US-20130109667-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109667-A1 | Chemical Compounds | SCN1A, SCN7A, SCN1B | SCN9A 11/4885CYP2C9 492/4885SCN5A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.