Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902334 | 1.00 | SYK (1.00) | SYK | |
| SCHEMBL14890162 | 1.00 | SYK (1.00) | SYK | |
| Hydrochloric Acid SCHEMBL14890477 | 0.99 | SYK (0.98) | SYK | |
| Hydrochloric Acid SCHEMBL14890476 | 0.99 | SYK (0.98) | SYK | |
| SCHEMBL14890735 | 0.99 | SYK (0.98) | SYK | |
| SCHEMBL14890260 | 0.94 | SYK (1.00) | SYK | |
| SCHEMBL14890369 | 0.94 | SYK (1.00) | SYK | |
| SCHEMBL14890304 | 0.94 | SYK (1.00) | SYK | |
| SCHEMBL14890259 | 0.94 | SYK (1.00) | SYK | |
| SCHEMBL14890601 | 0.93 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169259-B2 | Imidazopyridazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2015-10-27 | — | — | US | claimed |
| EP-2773645-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-09-10 | — | — | EP | claimed |
| WO-2013064445-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | claimed |
| US-20130109661-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-02 | — | — | US | claimed |
| US-9169259-B2 | Imidazopyridazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169259-B2 | Imidazopyridazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169259-B2 | Imidazopyridazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2773645-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064445-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-10 | — | — | WO | disclosed |
| US-20130109661-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109661-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109661-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109661-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | SYK, BTK, IRAK4 | SYK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.