⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488882 | 0.77 | — | — | |
| SCHEMBL8909852 | 0.75 | — | — | |
| SCHEMBL1964829 | 0.75 | NPSR1 (0.40) | — | |
| SCHEMBL7163871 | 0.73 | — | — | |
| SCHEMBL1489120 | 0.73 | — | — | |
| SCHEMBL11673924 | 0.71 | EHMT2 (0.36) | — | |
| SCHEMBL96554 | 0.71 | — | — | |
| SCHEMBL8663660 | 0.71 | — | — | |
| SCHEMBL11809610 | 0.71 | CA12 (0.45) | — | |
| SCHEMBL21051277 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| US-20210371416-A1 | NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUTED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2021-12-02 | — | — | US | disclosed |
| US-11066402-B2 | 3,5-disubstituted-3H-imidazo[4,5-b]pyridine and 3,5-disubstituted-3H-[1,2,3]triazolo[4,5-B] pyridine compounds as modulators of c-Met protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2021-07-20 | — | — | US | disclosed |
| EP-2831073-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES | RHIZEN PHARMACEUTICALS S A (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3459937-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | East China University of Science and Technology (CN) | 2019-03-27 | — | — | EP | disclosed |
| US-20180072721-A1 | NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5-DISUBSTITUTED-3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2018-03-15 | — | — | US | disclosed |
| US-9815831-B2 | 3,5-disubstituted-3H-imidazo[4,5-B]pyridine and 3,5-disubstituted-3H-[1,2,3]triazolo[4,5-B] pyridine compounds as modulators of c-Met protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2017-11-14 | — | — | US | disclosed |
| US-9388189-B2 | Pyrrolotriazinone derivatives as PI3K inhibitors | ALMIRALL, S.A. (ES) | 2016-07-12 | — | — | US | disclosed |
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | disclosed |
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |
| WO-2011069647-A1 | NEW 2-AMINOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-06-16 | — | — | WO | disclosed |
| EP-2305660-A1 | New thiadiazole derivatives | Almirall, S.A. (ES) | 2011-04-06 | — | — | EP | disclosed |
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |
| EP-2177521-A1 | New 2-Amidothiadiazole Derivatives | Almirall, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |
| EP-1979332-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007083089-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | WO | disclosed |