SCHEMBL14896

SCHEMBL14896

O=C1NCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 1.00
CA9 Q16790 1/20 1.00
PARP1 P09874 3/20 0.63
PDPK1 O15530 1/20 0.63
PARP10 Q53GL7 1/20 0.63
PARP11 Q9NR21 1/20 0.63
CLK4 Q9HAZ1 3/20 0.58
DYRK1B Q9Y463 3/20 0.58
NTRK2 Q16620 2/20 0.58
TYRO3 Q06418 1/20 0.58
GRM5 P41594 2/20 0.53
TDP2 O95551 1/20 0.52
CASP3 P42574 1/20 0.52
CASP7 P55210 1/20 0.52
CASP9 P55211 1/20 0.52
CASP6 P55212 1/20 0.52
CASP8 Q14790 1/20 0.52
MAP3K14 Q99558 1/20 0.52
KDR P35968 3/20 0.50
AURKA O14965 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355184 1.00 CA12 (1.00) CA12CA9PARP1PDPK1PARP10
SCHEMBL4818277 1.00 CA12 (1.00) CA12CA9PARP1PDPK1PARP10
SCHEMBL11354047 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Hydrochloric Acid SCHEMBL5046932 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Water SCHEMBL19462703 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
SCHEMBL8213864 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Water SCHEMBL19462706 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
SCHEMBL8213866 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Water SCHEMBL19462837 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
SCHEMBL1821811 0.98 CA12 (0.95) CA12CA9PARP1PDPK1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 51412 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423132-B1 None US claimed
US-12637410-B2 Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2026-05-26 US claimed
CN-121023676-B Method for producing colored nylon fiber based on online addition of oily 青岛润兴塑料新材料有限公司 2026-05-22 CN claimed
CN-122070323-A Electric automobile part 朗盛德国有限责任公司 2026-05-19 CN claimed
CN-122070336-A Electric automobile part 朗盛德国有限责任公司 2026-05-19 CN claimed
US-12629683-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2026-05-19 US claimed
WO-2026101929-A1 OPTICALLY TRANSPARENT POLYMER ELECTROLYTE FILMS DELSTAR TECHNOLOGIES, INC. (US) 2026-05-15 WO claimed
CN-122029158-A EGFR inhibitors 缆图药品公司 2026-05-12 CN claimed
US-20260126693-A1 OPTICALLY TRANSPARENT POLYMER ELECTROLYTE FILMS DELSTAR TECH INC (US) 2026-05-07 US claimed
EP-4731174-A1 COSMETIC COMPOSITION BASED ON CHITOSAN AND AT LEAST ONE CRYSTALLIZABLE FATTY COMPOUND L'OREAL (FR) 2026-04-29 EP claimed
US-4189423-A DIMENSIONAL STABILIZATION BY ADDING A DI(HALO-ISOINDOLO) AROMATIC COMPOUND OR MIXTURE WITH A PIGMENT TOYO INK MANUFACTURING CO., LTD. (JP) 1980-02-19 US claimed
US-4158661-A WITH AMMONIA OR AMINES CIBA-GEIGY CORPORATION (US) 1979-06-19 US claimed
US-4153800-A Isoindolinone pigments CIBA-GEIGY CORPORATION (US) 1979-05-08 US claimed
US-4097484-A ORGANIC PIGMENTS, PLASTICS CIBA-GEIGY CORPORATION (US) 1978-06-27 US claimed
US-4070367-A FASTNESS, YELLOW, PLASTICS, LACQUERS, PRINTING INKS CIBA-GEIGY CORPORATION (US) 1978-01-24 US claimed
US-4017448-A Transparent pigment dispersion process CELANESE COATINGS & SPECIALTIES COMPANY (US) 1977-04-12 US claimed
US-4002635-A FOR COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-01-11 US claimed
US-3997669-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1976-12-14 US claimed
US-3978080-A ANTIINFLAMMATORY, HYPOLIPIDEMIC CIBA-GEIGY CORPORATION (US) 1976-08-31 US claimed
US-3973981-A PHTHALOCYANINE DYES, PAINTS, INKS TOYO INK MANUFACTURING CO., LTD. (JA) 1976-08-10 US claimed