Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296682 | 1.00 | DPP4 (0.78) | DPP4DPP8 | |
| SCHEMBL14216808 | 1.00 | DPP4 (0.78) | DPP4DPP8 | |
| SCHEMBL17226208 | 1.00 | DPP4 (0.78) | DPP4DPP8 | |
| SCHEMBL17226189 | 0.88 | DPP4 (0.73) | DPP4 | |
| SCHEMBL14216803 | 0.88 | DPP4 (0.73) | DPP4 | |
| SCHEMBL14899531 | 0.88 | DPP4 (0.73) | DPP4 | |
| SCHEMBL17598269 | 0.88 | DPP4 (0.73) | DPP4 | |
| SCHEMBL14899044 | 0.88 | DPP4 (0.73) | DPP4 | |
| SCHEMBL10026718 | 0.79 | DPP4 (0.61) | DPP4 | |
| SCHEMBL896241 | 0.79 | DPP4 (0.61) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559710-B1 | Dipeptidyl peptidase IV inhibitors based on cyclopropyl-fused pyrrolidine, process for their preparation and their use | BRISTOL MYERS SQUIBB CO (US) | 2014-02-26 | — | — | EP | disclosed |
| US-RE44186-E1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-RE44186-E1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-30 | — | — | US | disclosed |