Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090110 | 0.93 | GCKR (0.47) | GCKRGCK | |
| SCHEMBL17109 | 0.93 | GCKR (0.57) | GCKRGCK | |
| SCHEMBL18627 | 0.90 | GCKR (0.54) | GCKRGCK | |
| SCHEMBL16634 | 0.88 | GCKR (0.58) | GCKRGCK | |
| SCHEMBL17705 | 0.87 | GCKR (0.63) | GCKRGCK | |
| SCHEMBL16625 | 0.86 | GCKR (0.62) | GCKRGCK | |
| Trifluoroacetic Acid SCHEMBL22992 | 0.86 | GCKR (0.57) | GCKRGCK | |
| SCHEMBL16057 | 0.86 | GCKR (0.59) | GCKRGCK | |
| SCHEMBL16124 | 0.85 | GCKR (0.61) | GCKRGCK | |
| SCHEMBL16568 | 0.85 | GCKR (0.65) | GCKRGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431563-B2 | Compounds that interact with glucokinase regulatory protein for the treatment of diabetes | AMGEN INC. (US) | 2013-04-30 | — | — | US | disclosed |