⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782493 | 1.00 | — | — | |
| SCHEMBL1781456 | 0.94 | HIF1A (0.33) | — | |
| SCHEMBL625882 | 0.94 | HIF1A (0.33) | — | |
| SCHEMBL1780706 | 0.94 | HIF1A (0.33) | — | |
| SCHEMBL12095338 | 0.94 | HIF1A (0.33) | — | |
| SCHEMBL284489 | 0.94 | — | — | |
| SCHEMBL6518187 | 0.92 | HIF1A (0.32) | — | |
| SCHEMBL1782807 | 0.89 | — | — | |
| SCHEMBL1864746 | 0.85 | — | — | |
| SCHEMBL1783195 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1982 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238304-A1 | Small Molecule Degraders of DOT1L and Uses Thereof | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | claimed |
| WO-2024149231-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| WO-2024149234-A1 | PARP7 INHIBITORS AND USES THEREOF | Angel Pharmaceutical Co., Ltd. (CN) | 2024-07-18 | — | — | WO | claimed |
| US-20240238423-A9 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. | 2024-07-18 | — | — | US | claimed |
| WO-2024149239-A1 | HETEROAROMATIC CYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2024-07-18 | — | — | WO | claimed |
| WO-2024140595-A1 | TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 珂阑(上海)医药科技有限公司 | 2024-07-04 | — | — | WO | claimed |
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-114181205-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| WO-2024114781-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | 上海日馨医药科技股份有限公司 | 2024-06-06 | — | — | WO | claimed |
| WO-2024118810-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | claimed |
| EP-0258923-A2 | Fabric softening composition and detergent-composition comprising the same | Akzo Nobel N.V. (NL) | 1988-03-09 | — | — | EP | claimed |
| EP-0075849-B1 | TRIAZINYLLACTAMES, PROCESS FOR THEIR PREPARATION, THEIR USE AS STABILISATORS FOR SYNTHETIC ORGANIC POLYMERS AND POLYMERS STABILISED BY THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | claimed |
| EP-0065169-B1 | POLY-BIS-TRIAZINYLAMINOTRIAZINYL AMINES, THEIR PREPARATION, THEIR USE AS STABILISERS FOR PLASTICS AGAINST LIGHT DEGRADATION AND PLASTICS STABILIZED BY THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-23 | — | — | EP | claimed |
| EP-0068083-B1 | POLY-BIS-TRIAZINYL IMIDE, ITS PREPARATION AND ITS USE AS A LIGHT-STABILISER FOR POLYMERS, AS WELL AS THE POLYMERS STABILISED THEREWITH | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-14 | — | — | EP | claimed |
| EP-0053775-B1 | POLY-BIS-TRIAZYNYL AMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN STABILISING SYNTHETIC POLYMERS, AND POLYMERS STABILISED THIS WAY | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-07 | — | — | EP | claimed |
| EP-0052300-B1 | C-3-LINKED 1,4-DIHYDROPYRIDINES, THEIR USE IN PHARMACEUTICAL PREPARATIONS AND PROCESSES FOR THEIR PREPARATION | BAYER AG (DE) | 1985-02-13 | — | — | EP | claimed |
| US-4471417-A | LIGHT STABILIZERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | claimed |
| EP-0087564-A1 | Specific binding assay method, reagent system and labelled conjugate for use in this method | MILES LABORATORIES, INC. (US) | 1983-09-07 | — | — | EP | claimed |
| EP-0052300-A1 | C-3-linked 1,4-dihydropyridines, their use in pharmaceutical preparations and processes for their preparation | BAYER AG (DE) | 1982-05-26 | — | — | EP | claimed |
| US-4270918-A | METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE | CIBA-GEIGY CORPORATION (US) | 1981-06-02 | — | — | US | claimed |