Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216686 | 1.00 | DPP4 (0.55) | DPP4DPP8DPP9FAP | |
| SCHEMBL14899028 | 0.82 | DPP4 (0.81) | DPP4 | |
| SCHEMBL14899610 | 0.82 | DPP4 (0.81) | DPP4 | |
| SCHEMBL12937403 | 0.82 | DPP4 (0.81) | DPP4 | |
| SCHEMBL17226168 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9FAP | |
| SCHEMBL14899617 | 0.78 | DPP4 (0.46) | DPP4DPP8DPP9FAP | |
| SCHEMBL15492505 | 0.76 | DPP4 (0.43) | DPP4FAP | |
| SCHEMBL10289931 | 0.76 | DPP4 (0.69) | DPP4 | |
| SCHEMBL17598290 | 0.76 | DPP4 (0.43) | DPP4FAP | |
| SCHEMBL17690943 | 0.76 | DPP4 (0.69) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44186-E1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-30 | — | — | US | disclosed |