Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489940 | 0.88 | ADORA2A (0.67) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1490249 | 0.87 | ADORA2A (0.60) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1489759 | 0.82 | ADORA2A (0.76) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1490002 | 0.81 | ADORA2A (0.60) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1489629 | 0.79 | ADORA2A (0.76) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1489524 | 0.78 | ADORA2A (0.78) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1490023 | 0.78 | ADORA2A (0.77) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1489699 | 0.78 | ADORA2A (0.77) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1489516 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1KCNH2 | |
| SCHEMBL1490078 | 0.77 | ADORA2A (0.98) | ADORA2AADORA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888565-B1 | 2, 6-DI (HETERO) ARYL -4-AMIDO-PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL SA (ES) | 2011-03-23 | — | — | EP | claimed |
| EP-1888565-B1 | 2, 6-DI (HETERO) ARYL -4-AMIDO-PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL SA (ES) | 2011-03-23 | — | — | EP | disclosed |