Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 13/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16800371 | 0.92 | P2RY12 (0.40) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL4948776 | 0.90 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL2412436 | 0.90 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL4950559 | 0.90 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL2130983 | 0.90 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL2612406 | 0.90 | P2RY12 (0.49) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL1834983 | 0.90 | P2RY12 (0.48) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL29688130 | 0.90 | P2RY12 (0.48) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL14889079 | 0.90 | P2RY12 (0.48) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL17249645 | 0.89 | P2RY12 (0.41) | P2RY12PGRADORA3CHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586773-A1 | Synthesis of Triazolopyrimidine Compounds | LEK Pharmaceuticals d.d. (SI) | 2013-05-01 | — | — | EP | disclosed |