Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12830862 | 0.92 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5KDM4E | |
| SCHEMBL1489267 | 0.91 | S1PR1 (0.63) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1490276 | 0.91 | S1PR1 (0.51) | S1PR1S1PR3S1PR4S1PR5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1490127 | 0.91 | S1PR1 (0.62) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1490262 | 0.90 | S1PR1 (0.49) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL12830860 | 0.90 | S1PR1 (0.51) | S1PR1S1PR3 | |
| SCHEMBL12831153 | 0.89 | S1PR1 (0.51) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488953 | 0.86 | S1PR1 (0.68) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1489118 | 0.85 | S1PR1 (0.63) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1489168 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035900-A1 | NEW THIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-03-31 | — | — | WO | disclosed |