SCHEMBL14902801

SCHEMBL14902801

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nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.56
L3MBTL1 Q9Y468 1/20 0.42
NEU1 Q99519 2/20 0.33
SELL P14151 1/20 0.32
SELP P16109 1/20 0.32
MAG P20916 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14944648 0.89 NANP (0.42) NANPNEU1MAG
Sialic Acid SCHEMBL28021266 0.85 NANP (0.58) NANPL3MBTL1NEU1SELLSELP
SCHEMBL20190565 0.84 NANP (0.67) NANPL3MBTL1NEU1SELLSELP
SCHEMBL420656 0.84 NANP (0.67) NANPL3MBTL1NEU1SELLSELP
SCHEMBL13190787 0.84 NANP (0.67) NANPL3MBTL1NEU1SELLSELP
SCHEMBL29632786 0.84 NANP (0.67) NANPL3MBTL1NEU1SELLSELP
SCHEMBL29390472 0.84 NANP (0.67) NANPL3MBTL1NEU1SELLSELP
SCHEMBL27909377 0.82 NANP (0.65) NANPL3MBTL1NEU1SELLSELP
SCHEMBL8662575 0.82 NANP (0.65) NANPL3MBTL1NEU1SELLSELP
SCHEMBL30887281 0.81 NANP (0.69) NANPL3MBTL1SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889607-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2021-01-12 US disclosed
US-20200131215-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. 2020-04-30 US disclosed
US-10457701-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2019-10-29 US disclosed
US-20190127409-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. 2019-05-02 US disclosed
US-20160297846-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2016-10-13 US disclosed
US-9221858-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-12-29 US disclosed
US-20150038693-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-02-05 US disclosed
US-8840926-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2014-09-23 US disclosed
US-20130122094-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-16 US disclosed
WO-2013063149-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457701-B2 Sialic acid analogs NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-20200131215-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-20160297846-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-20130122094-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-20150038693-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-10889607-B2 Sialic acid analogs NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885
US-20190127409-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885L3MBTL1 1717/4885NEU1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.