SCHEMBL14902808

SCHEMBL14902808

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nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.48
MAG P20916 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
NEU1 Q99519 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14902819 0.93 NANP (0.48) NANPMAGL3MBTL1NEU1
SCHEMBL14902817 0.90 NANP (0.45) NANPMAGL3MBTL1NEU1
SCHEMBL20968002 0.90 NANP (0.61) NANPMAGL3MBTL1NEU1
SCHEMBL14902803 0.90 NANP (0.61) NANPMAGL3MBTL1NEU1
SCHEMBL21939236 0.88 NANP (0.45) NANPMAGL3MBTL1
SCHEMBL14944644 0.85 NANP (0.46) NANPMAGNEU1
SCHEMBL20544409 0.84 NANP (0.55) NANPMAGL3MBTL1NEU1
SCHEMBL988713 0.84 NANP (0.55) NANPMAGL3MBTL1NEU1
SCHEMBL18137162 0.83 NANP (0.47) NANPMAGL3MBTL1NEU1
SCHEMBL27909377 0.79 NANP (0.65) NANPMAGL3MBTL1NEU1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889607-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2021-01-12 US disclosed
US-20200131215-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. 2020-04-30 US disclosed
US-10457701-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2019-10-29 US disclosed
US-20190127409-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. 2019-05-02 US disclosed
US-20160297846-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2016-10-13 US disclosed
US-9221858-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-12-29 US disclosed
US-20150038693-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2015-02-05 US disclosed
US-8840926-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2014-09-23 US disclosed
US-20130122094-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-16 US disclosed
WO-2013063149-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457701-B2 Sialic acid analogs NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-20200131215-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-20160297846-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-20130122094-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-20150038693-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-10889607-B2 Sialic acid analogs NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885
US-20190127409-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 NANP 37/4885MAG 768/4885L3MBTL1 1717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.