Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.69 |
| ▸ | FGFR2 | P21802 | 20/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 20/20 | 0.69 |
| ▸ | FGFR3 | P22607 | 20/20 | 0.69 |
| ▸ | KDR | P35968 | 20/20 | 0.69 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808368 | 0.87 | FGFR1 (0.66) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905563 | 0.85 | FGFR1 (0.80) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL16523114 | 0.81 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL18346569 | 0.79 | FGFR1 (0.77) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905541 | 0.79 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20808255 | 0.75 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20309568 | 0.74 | FGFR3 (0.49) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905544 | 0.74 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL16523112 | 0.73 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14901292 | 0.72 | FGFR1 (0.62) | FGFR1FGFR2FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013061077-A1 | NEW COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2013-05-02 | — | — | WO | disclosed |