⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002040 | 0.80 | — | — | |
| SCHEMBL6284366 | 0.79 | — | — | |
| SCHEMBL23731655 | 0.73 | — | — | |
| SCHEMBL284681 | 0.71 | — | — | |
| SCHEMBL10904378 | 0.71 | — | — | |
| SCHEMBL16672175 | 0.71 | — | — | |
| SCHEMBL22131014 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL28112622 | 0.68 | KDM4E (0.53) | — | |
| Hydrochloric Acid SCHEMBL10804922 | 0.68 | KDM4E (0.53) | — | |
| SCHEMBL27586898 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220025397-A1 | LIGAND-DIRECTED TARGETING VECTORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-27 | — | — | US | disclosed |
| US-8476308-B2 | GPR120 receptor agonists and uses thereof | METABOLEX, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20130131351-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130109734-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2013-05-02 | — | — | US | disclosed |