Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704321 | 0.91 | CYP3A4 (0.45) | TSHRCYP3A4L3MBTL1 | |
| SCHEMBL1296634 | 0.81 | TSHR (0.65) | TSHRCYP3A4L3MBTL1TP53TDP1 | |
| SCHEMBL3823280 | 0.81 | TSHR (0.65) | TSHRCYP3A4L3MBTL1TP53TDP1 | |
| Tris(2,3-Dibromopropyl)Phosphate SCHEMBL5908710 | 0.78 | TSHR (0.54) | TSHRCYP3A4L3MBTL1TP53TDP1 | |
| SCHEMBL22578282 | 0.77 | TSHR (0.59) | TSHRCYP3A4L3MBTL1TP53TDP1 | |
| Triethyl Phosphate SCHEMBL28023664 | 0.77 | TSHR (1.00) | TSHRCYP3A4TP53TDP1PPARD | |
| Triethyl Phosphate SCHEMBL21887 | 0.77 | TSHR (1.00) | TSHRCYP3A4TP53TDP1PPARD | |
| Triethyl Phosphate SCHEMBL1332591 | 0.77 | TSHR (1.00) | TSHRCYP3A4TP53TDP1PPARD | |
| Triethyl Phosphate SCHEMBL27822049 | 0.77 | TSHR (1.00) | TSHRCYP3A4TP53TDP1PPARD | |
| SCHEMBL19857469 | 0.74 | TSHR (0.62) | TSHRCYP3A4L3MBTL1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110054188-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289563-A1 | Near infrared fluorescent imaging agent | Fujifilm Corporation (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054188-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | MSR1, IK, RXFP1 | TSHR 394/4885CYP3A4 3723/4885L3MBTL1 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.