Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL14895875 | 0.88 | GRM4 (0.52) | GRM4FADS1 | |
| SCHEMBL14906049 | 0.87 | GRM4 (0.67) | GRM4 | |
| SCHEMBL14896339 | 0.83 | GRM4 (0.64) | GRM4FADS1 | |
| SCHEMBL14906082 | 0.82 | GRM4 (0.60) | GRM4FADS1 | |
| SCHEMBL14906217 | 0.80 | GRM4 (0.60) | GRM4FADS1 | |
| SCHEMBL6922917 | 0.78 | GRM4 (1.00) | GRM4 | |
| SCHEMBL14867351 | 0.76 | GRM4 (0.85) | GRM4 | |
| SCHEMBL14906200 | 0.75 | GRM4 (0.54) | GRM4FADS1 | |
| Trifluoroacetic Acid SCHEMBL14895956 | 0.73 | GRM4 (0.49) | GRM4FADS1 | |
| Trifluoroacetic Acid SCHEMBL14896089 | 0.73 | GRM4 (0.52) | GRM4FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063100-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-02 | — | — | WO | disclosed |