Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490872 | 0.95 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL1490552 | 0.89 | TLR7 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL2892888 | 0.87 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL1490737 | 0.86 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL4594484 | 0.84 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL1490813 | 0.84 | TLR7 (0.60) | TLR7TLR8NUDT1 | |
| SCHEMBL1490860 | 0.83 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL2896460 | 0.83 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL3872419 | 0.83 | TLR7 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL1490824 | 0.83 | TLR7 (0.53) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598192-B2 | Hydroxylamine substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-03 | — | — | US | disclosed |
| US-7897767-B2 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |