Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615242 | 0.83 | CHRM1 (0.49) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL13196104 | 0.80 | HRH1 (0.75) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL13760219 | 0.80 | HRH1 (0.75) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL8985501 | 0.75 | PDE5A (0.40) | CHRM1LMNAADRA1AKCNH2SRC | |
| SCHEMBL27391010 | 0.74 | TSHR (0.42) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL4662568 | 0.73 | CHRM1 (0.81) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL8750430 | 0.72 | SRC (0.36) | CHRM1LMNAADRA1ASRCPOLB | |
| SCHEMBL8766798 | 0.72 | SRC (0.45) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL22425523 | 0.72 | SRC (0.33) | CHRM1LMNACHRM2CHRM5CHRM3 | |
| SCHEMBL7813526 | 0.71 | KMT2A (0.50) | LMNAPOLBKMT2AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063269-A2 | COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |