Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FER | P16591 | 6/20 | 0.61 |
| ▸ | SYK | P43405 | 11/20 | 0.56 |
| ▸ | CAMK1D | Q8IU85 | 4/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | HCK | P08631 | 1/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | MARK3 | P27448 | 1/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.55 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910837 | 1.00 | FER (0.61) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL14929774 | 1.00 | FER (0.61) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL16164427 | 0.91 | SYK (0.59) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL5027524 | 0.89 | SYK (0.66) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL14910271 | 0.87 | FER (0.65) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL5027513 | 0.87 | FER (0.65) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL20750794 | 0.87 | FER (0.65) | FERSYKCAMK1DPIM1JAK2 | |
| SCHEMBL14909384 | 0.87 | SYK (0.53) | FERSYK | |
| SCHEMBL14909381 | 0.87 | SYK (0.53) | FERSYK | |
| SCHEMBL9106025 | 0.87 | FER (0.79) | FERSYKPIM1JAK2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |