Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335826 | 0.83 | PTGDR2 (0.46) | PTGDR2CASP3 | |
| SCHEMBL2330878 | 0.82 | PTGDR2 (0.43) | PTGDR2CASP3 | |
| SCHEMBL14914629 | 0.82 | KDM4E (0.39) | PTGDR2CASP3 | |
| SCHEMBL14914128 | 0.80 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL14938843 | 0.79 | PTGDR2 (0.39) | PTGDR2CASP3 | |
| SCHEMBL709958 | 0.78 | PTGDR2 (0.45) | PTGDR2CASP3 | |
| SCHEMBL710245 | 0.75 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL2339250 | 0.75 | PTGDR2 (0.41) | PTGDR2CASP3 | |
| SCHEMBL9009204 | 0.74 | AVPR1B (0.43) | PTGDR2 | |
| SCHEMBL15207964 | 0.74 | PTGDR2 (0.57) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470884-B2 | Alkenyl naphthylacetic acids | HOFFMANN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470884-B2 | Alkenyl naphthylacetic acids | HOFFMANN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470884-B2 | Alkenyl naphthylacetic acids | HOFFMANN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | disclosed |
| WO-2013068322-A1 | ALKENYL NAPHTHYLACETIC ACIDS FOR TREATING RESPIRATORY DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013068322-A1 | ALKENYL NAPHTHYLACETIC ACIDS FOR TREATING RESPIRATORY DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-16 | — | — | WO | disclosed |
| US-20130116322-A1 | ALKENYL NAPHTHYLACETIC ACIDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-20130116322-A1 | ALKENYL NAPHTHYLACETIC ACIDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-20130116322-A1 | ALKENYL NAPHTHYLACETIC ACIDS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116322-A1 | ALKENYL NAPHTHYLACETIC ACIDS | HRH2, HRH1, HRH3 | PTGDR2 44/4885CASP3 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.