Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918513 | 0.92 | HDAC6 (0.52) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14917978 | 0.92 | HDAC6 (0.62) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918425 | 0.91 | HDAC6 (0.48) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918174 | 0.91 | HDAC6 (0.49) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918666 | 0.89 | HDAC6 (0.50) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918309 | 0.84 | HDAC6 (0.51) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14917924 | 0.84 | HDAC6 (0.48) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918055 | 0.83 | HDAC6 (0.50) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14918902 | 0.83 | HDAC6 (0.49) | HDAC6HDAC8HDAC1HDAC4HDAC3 | |
| SCHEMBL14917887 | 0.83 | HDAC6 (0.49) | HDAC6HDAC8HDAC1HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066831-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |