Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918385 | 0.90 | HDAC6 (0.57) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918810 | 0.90 | HDAC6 (0.59) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918075 | 0.86 | HDAC4 (0.63) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14917846 | 0.85 | HDAC4 (0.59) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14917886 | 0.85 | HDAC4 (0.58) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918720 | 0.84 | HDAC4 (0.57) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918631 | 0.84 | HDAC4 (0.57) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918254 | 0.84 | HDAC4 (0.53) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918314 | 0.83 | HDAC4 (0.56) | HDAC6HDAC1HDAC4HDAC5HDAC7 | |
| SCHEMBL14918482 | 0.82 | HDAC4 (0.55) | HDAC6HDAC1HDAC4HDAC5HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |