Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918378 | 0.88 | HDAC6 (0.47) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918760 | 0.87 | HDAC6 (0.47) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918710 | 0.86 | HDAC6 (0.57) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918595 | 0.86 | HDAC6 (0.47) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918380 | 0.84 | HDAC6 (0.46) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918826 | 0.83 | HDAC6 (0.59) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918763 | 0.82 | HDAC4 (0.55) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918597 | 0.82 | HDAC6 (0.50) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14918261 | 0.81 | HDAC6 (0.52) | HDAC6HDAC1HDAC4HDAC8HDAC5 | |
| SCHEMBL14917958 | 0.80 | HDAC6 (0.55) | HDAC6HDAC1HDAC4HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |