Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918426 | 1.00 | HDAC1 (0.50) | HDAC1HDAC2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14918873 | 0.99 | HDAC1 (0.48) | HDAC1HDAC2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14918752 | 0.88 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1MAPTGAA | |
| SCHEMBL14918400 | 0.88 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1MAPTGAA | |
| SCHEMBL14918841 | 0.88 | HDAC1 (0.51) | HDAC1HDAC2ALDH1A1MAPTGAA | |
| SCHEMBL14917815 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1HDAC6HDAC4 | |
| SCHEMBL14917884 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1HDAC6HDAC4 | |
| SCHEMBL14918023 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1HDAC6HDAC4 | |
| SCHEMBL14919136 | 0.87 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1MAPTGAA | |
| SCHEMBL14917792 | 0.86 | HDAC1 (0.53) | HDAC1HDAC2ALDH1A1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |