Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 18/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918180 | 0.79 | HDAC4 (0.58) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14917909 | 0.79 | HDAC4 (0.79) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918839 | 0.78 | HDAC4 (0.62) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918762 | 0.78 | HDAC4 (0.50) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918231 | 0.77 | HDAC4 (0.42) | HDAC4HDAC6HDAC1CNR2 | |
| SCHEMBL14918090 | 0.77 | HDAC6 (0.43) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918565 | 0.76 | HDAC4 (0.51) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918259 | 0.75 | HDAC6 (0.41) | HDAC4HDAC6HDAC1CNR2 | |
| SCHEMBL14918272 | 0.75 | HDAC6 (0.42) | HDAC4HDAC6HDAC1 | |
| SCHEMBL14918572 | 0.75 | P4HTM (0.43) | HDAC4HDAC6HDAC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066835-A2 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |