SCHEMBL1491920

SCHEMBL1491920

CC(=O)CCC(=O)O[C@H]1[C@@H](OC(=N)C(Cl)(Cl)Cl)O[C@H](C)[C@@H](ON=[N+]=[N-])[C@@H]1OCc1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGF2 P09038 1/20 0.31
MDK P21741 1/20 0.31
PDPK1 O15530 1/20 0.31
MTOR P42345 1/20 0.31
NT5E P21589 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1975347 0.91 NT5E (0.34) FGF2MDKPDPK1MTORNT5E
SCHEMBL15654703 0.86 FGF2 (0.39) FGF2MDKNT5E
SCHEMBL13129896 0.86 FGF2 (0.35) FGF2MDKNT5E
SCHEMBL15975393 0.86 FGF2 (0.35) FGF2MDKNT5E
SCHEMBL1491955 0.83 PDPK1 (0.36) FGF2MDKPDPK1MTOR
SCHEMBL1491923 0.82 FGF2 (0.43) FGF2MDKPDPK1MTOR
SCHEMBL1973777 0.81 NT5E (0.36) FGF2PDPK1MTORNT5E
SCHEMBL1034819 0.81 NT5E (0.37) PDPK1MTORNT5E
SCHEMBL12757246 0.81 NT5E (0.37) PDPK1MTORNT5E
SCHEMBL22423316 0.81 NT5E (0.37) PDPK1MTORNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7901687-B2 Antibodies for the detection of Bacillus anthracis and vaccine against B. anthracis infections ETH ZURICH (CH) 2011-03-08 US disclosed
US-20090155299-A1 Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections SCHWEIZERISCHES TROPENINSTITUT (CH) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155299-A1 Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections ANTXR2, CERT1, DAD1 FGF2 2980/4885MDK 3902/4885PDPK1 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.