⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62663 | 1.00 | — | — | |
| SCHEMBL8731 | 0.94 | — | — | |
| SCHEMBL8535919 | 0.94 | — | — | |
| SCHEMBL4536882 | 0.89 | — | — | |
| SCHEMBL10486847 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL9833805 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL917369 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL6028938 | 0.89 | — | — | |
| SCHEMBL4443012 | 0.89 | — | — | |
| SCHEMBL11243979 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788326-B1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RES & DEV (FR) | 2019-04-24 | — | — | EP | disclosed |
| US-9732044-B2 | N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-08-15 | — | — | US | disclosed |
| US-20170066725-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-03-09 | — | — | US | disclosed |
| US-9452120-B2 | N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-09-27 | — | — | US | disclosed |
| EP-2788326-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | Galderma Research & Development (FR) | 2014-10-15 | — | — | EP | disclosed |
| US-20140234245-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-08-21 | — | — | US | disclosed |
| WO-2013064681-A1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-05-10 | — | — | WO | disclosed |