Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14885500 | 0.78 | KDM1A (0.55) | KDM1AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL25058901 | 0.78 | HTR2C (0.59) | KDM1AHTR2CHTR2AHTR2BSLC6A2 | |
| Hydrochloric Acid SCHEMBL4138349 | 0.77 | KDM1A (0.54) | KDM1AHTR2CHTR2BMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4139365 | 0.77 | KDM1A (0.56) | KDM1AHTR2CHTR2AHTR2BSLC6A2 | |
| SCHEMBL29357722 | 0.73 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL14880273 | 0.73 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL14880558 | 0.73 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL16019216 | 0.73 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL14882080 | 0.73 | KDM1A (1.00) | KDM1AHTR2CHTR2ASLC6A2SLC6A4 | |
| SCHEMBL14880544 | 0.73 | KDM1A (1.00) | KDM1AHTR2CHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773616-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064520-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |