Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524078 | 0.93 | ELANE (0.64) | ELANEMEN1KMT2ACTSKCYP3A4 | |
| SCHEMBL1603366 | 0.92 | ELANE (0.59) | ELANEMEN1KMT2ACTSK | |
| SCHEMBL1604022 | 0.92 | ELANE (0.61) | ELANEMEN1KMT2ACYP2C9 | |
| Iodide SCHEMBL1603408 | 0.92 | ELANE (0.60) | ELANEMEN1KMT2ACYP2C9 | |
| SCHEMBL597096 | 0.91 | ELANE (0.61) | ELANEMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL597440 | 0.91 | ELANE (0.63) | ELANEMEN1KMT2ACYP3A4CYP2C9 | |
| Acetic Acid SCHEMBL1603082 | 0.90 | ELANE (0.58) | ELANEMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL525061 | 0.89 | ELANE (0.74) | ELANEMEN1KMT2ACTSKCYP3A4 | |
| SCHEMBL595623 | 0.88 | ELANE (0.60) | ELANEMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL597381 | 0.87 | ELANE (0.62) | ELANEMEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436024-B2 | 2-pyridone compounds | ASTRAZENECA AB (GB) | 2013-05-07 | — | — | US | disclosed |