Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922593 | 0.98 | SCN9A (0.41) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL15381730 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL14766323 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL12741066 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL15381537 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL12737602 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL14767196 | 0.96 | SCN9A (0.40) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL14767242 | 0.95 | SCN9A (0.39) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL14766049 | 0.95 | SCN9A (0.39) | SCN9ACNR2CNR1GRM2TSHR | |
| SCHEMBL12197191 | 0.95 | SCN9A (0.39) | SCN9ACNR2CNR1GRM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |