Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240560 | 1.00 | ALOX5AP (0.37) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL1240559 | 1.00 | ALOX5AP (0.37) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL14922536 | 0.97 | ALOX5AP (0.38) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL15381688 | 0.95 | FEN1 (0.39) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL15381723 | 0.95 | FEN1 (0.39) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL2509013 | 0.94 | ALOX5AP (0.36) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL2509015 | 0.94 | ALOX5AP (0.36) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL14922662 | 0.94 | ALOX5AP (0.37) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL14766949 | 0.93 | ALOX5AP (0.34) | ALOX5APFEN1SCN9AHTR2AHTR2C | |
| SCHEMBL12735788 | 0.93 | SCN9A (0.41) | ALOX5APFEN1SCN9AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |