Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15381719 | 0.96 | HPGD (0.40) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL15381586 | 0.96 | HPGD (0.40) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14922562 | 0.94 | HPGD (0.42) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14922676 | 0.94 | HPGD (0.47) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14922584 | 0.93 | HPGD (0.39) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14922670 | 0.92 | SCN9A (0.41) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14767287 | 0.91 | HPGD (0.43) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14766044 | 0.91 | HPGD (0.43) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL15381795 | 0.90 | HPGD (0.40) | HPGDSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL15381710 | 0.90 | HPGD (0.40) | HPGDSMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |