Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001496 | 0.92 | HRH4 (0.58) | HRH4HRH3HTR3ANUDT1 | |
| SCHEMBL2492711 | 0.90 | HRH4 (0.55) | HRH4NUDT1 | |
| SCHEMBL2993600 | 0.86 | HRH4 (0.55) | HRH4NUDT1 | |
| SCHEMBL2515479 | 0.85 | HRH4 (0.50) | HRH4NUDT1 | |
| SCHEMBL2992854 | 0.84 | HRH4 (0.48) | HRH4 | |
| SCHEMBL2992853 | 0.84 | HRH4 (0.48) | HRH4 | |
| SCHEMBL3000217 | 0.82 | HRH4 (0.55) | HRH4HRH3HTR3ANUDT1 | |
| SCHEMBL15254643 | 0.82 | HRH4 (0.55) | HRH4HRH3HTR3ANUDT1 | |
| SCHEMBL2516072 | 0.82 | HRH4 (0.55) | HRH4HRH3HTR3A | |
| SCHEMBL2536464 | 0.82 | HRH4 (0.51) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436008-B2 | Substituted heterocyclic compounds | INCYTE CORPORATION (US) | 2013-05-07 | — | — | US | disclosed |