Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636026 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL636028 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL636027 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL2537722 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL2537720 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL2543521 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL1937063 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL2543519 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL2537724 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC4HDAC3HDAC7 | |
| SCHEMBL1936790 | 0.85 | HDAC1 (0.37) | HDAC1HDAC8HDAC4HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331553-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-05-08 | — | — | EP | disclosed |