Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 18/20 | 0.59 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | FER | P16591 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14928778 | 1.00 | SYK (0.59) | SYKEML4ALKFERBTK | |
| SCHEMBL14909418 | 1.00 | SYK (0.59) | SYKEML4ALKFERBTK | |
| SCHEMBL14909414 | 1.00 | SYK (0.59) | SYKEML4ALKFERBTK | |
| SCHEMBL14928750 | 0.99 | SYK (0.57) | SYKEML4ALKFERKCNH2 | |
| SCHEMBL14909402 | 0.99 | SYK (0.57) | SYKEML4ALKFERKCNH2 | |
| SCHEMBL14909399 | 0.99 | SYK (0.57) | SYKEML4ALKFERKCNH2 | |
| SCHEMBL14908988 | 0.93 | SYK (0.65) | SYKEML4ALKBTKKCNH2 | |
| SCHEMBL14908991 | 0.93 | SYK (0.65) | SYKEML4ALKBTKKCNH2 | |
| SCHEMBL14929192 | 0.93 | SYK (0.65) | SYKEML4ALKBTKKCNH2 | |
| SCHEMBL14923629 | 0.93 | SYK (0.54) | SYKEML4ALKFERKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |