Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 19/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923873 | 1.00 | SYK (0.37) | SYKAURKBZAP70AAK1 | |
| SCHEMBL16170911 | 0.95 | SYK (0.35) | SYKAAK1 | |
| SCHEMBL14923712 | 0.95 | SYK (0.35) | SYKAAK1 | |
| SCHEMBL14931154 | 0.94 | ITK (0.36) | SYK | |
| SCHEMBL14923913 | 0.93 | SYK (0.33) | SYKZAP70AAK1 | |
| SCHEMBL14923912 | 0.93 | SYK (0.33) | SYKAAK1 | |
| SCHEMBL16170834 | 0.91 | SYK (0.36) | SYKAAK1 | |
| SCHEMBL16170952 | 0.91 | SYK (0.37) | SYKAAK1 | |
| SCHEMBL3346241 | 0.91 | SYK (0.32) | SYK | |
| SCHEMBL16170849 | 0.89 | SYK (0.35) | SYKAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |