Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.46 |
| ▸ | FER | P16591 | 5/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929328 | 1.00 | SYK (0.46) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14923756 | 0.92 | SYK (0.48) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14931149 | 0.92 | SYK (0.48) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14929307 | 0.91 | FER (0.49) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14929503 | 0.87 | SYK (0.52) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14908739 | 0.86 | FER (0.53) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14908737 | 0.86 | FER (0.53) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14909853 | 0.85 | FER (0.49) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14929954 | 0.85 | FER (0.49) | SYKFERMAPK3MAPK1KCNH2 | |
| SCHEMBL14923887 | 0.85 | FER (0.49) | SYKFERMAPK3MAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |