Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.55 |
| ▸ | FER | P16591 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910080 | 1.00 | SYK (0.55) | SYKFERKCNH2 | |
| SCHEMBL14910079 | 1.00 | SYK (0.55) | SYKFERKCNH2 | |
| SCHEMBL14910540 | 0.89 | SYK (0.57) | SYKKCNH2 | |
| SCHEMBL14910539 | 0.89 | SYK (0.57) | SYKKCNH2 | |
| SCHEMBL14910784 | 0.89 | SYK (0.60) | SYKKCNH2 | |
| SCHEMBL14910785 | 0.89 | SYK (0.60) | SYKKCNH2 | |
| SCHEMBL14929350 | 0.88 | SYK (0.61) | SYKFERKCNH2 | |
| SCHEMBL9103476 | 0.88 | SYK (0.61) | SYKFERKCNH2 | |
| SCHEMBL14909805 | 0.88 | SYK (0.61) | SYKFERKCNH2 | |
| SCHEMBL14911309 | 0.88 | SYK (0.60) | SYKFERKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |