Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | FGR | P09769 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.48 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PAK5 | Q9P286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909231 | 1.00 | SYK (0.61) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14909230 | 1.00 | SYK (0.61) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14908813 | 0.91 | SYK (0.61) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14928936 | 0.91 | SYK (0.61) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14908811 | 0.91 | SYK (0.61) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14910421 | 0.89 | SYK (0.58) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14910423 | 0.89 | SYK (0.58) | SYKJAK2LCKYES1LYN | |
| SCHEMBL9103435 | 0.88 | SYK (0.72) | SYKKCNH2 | |
| SCHEMBL9106690 | 0.87 | SYK (0.74) | SYKJAK2LCKYES1LYN | |
| SCHEMBL14911331 | 0.86 | SYK (0.61) | SYKJAK2LCKYES1LYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |