Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19790456 | 0.89 | SYK (0.48) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL14910350 | 0.88 | SYK (0.55) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL13074772 | 0.88 | SYK (0.54) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL10250632 | 0.84 | SYK (0.53) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL9108358 | 0.83 | SYK (0.58) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL5026970 | 0.83 | SYK (0.58) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL14908667 | 0.83 | SYK (0.52) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL14909181 | 0.83 | SYK (0.52) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL2713766 | 0.83 | SYK (0.56) | SYKNPC1MAPTPOLBMEN1 | |
| SCHEMBL14909464 | 0.83 | SYK (0.54) | SYKNPC1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |